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Glossy, trendy and a household name, Prozac has become the first prescription drug of our time to transgress the obscure world of medical textbooks and enter the glamorized sphere of popular culture.
And yet the drug's success may not be quite so straightforward.
With growing controversy surrounding Prozac and the emergence of similar anti-depressants, the first quarter of this year -- 15 years after Prozac first hit the market -- has seen the pharmaceutical giant Eli Lilly and Co., manufacturer of Prozac, report an astounding 25-percent drop in earnings.
While some are blaming this drop on Lilly's loss of its patent and the corresponding emergence of less expensive generic versions, others identify another phenomenon: the end of the "happy pill" era.
Once considered a wonder drug, Prozac was believed to be a much more viable, efficient and inexpensive alternative to psychotherapy.
But after 15 years on the market, scientists are now beginning to understand the long-term effects of the drug and why therapy may, many say, be much more beneficial than a prescription.
Approved by the Food and Drug Administration in 1987 as an anti-depressant with "fewer than usual" side effects, Prozac (or fluoxetine) became widely used for treating depression, obsessive-compulsive disorder and bulimia nervosa.
Within two years, pharmacies were filling out 65,000 Prozac prescriptions a month in the United States alone.